Which ingredients work best with tranexamic acid?

Among the many whitening active ingredients, tranexamic acid is often mentioned.

Tranexamic acid is also called tranexamic acid, and tranexamic acid is its standard Chinese name in the “Catalogue of Names of Used Cosmetic Raw Materials (2015 Edition)”.

The whitening mechanism of tranexamic acid is quite different from other ingredients, mainly related to its blood clotting mechanism. There is a protease in serum called PA (plasminogen activator), which can make blood flow smoothly and is also related to the activation of melanocytes, and tranexamic acid can inhibit it.

Whitening ingredients are usually combined to achieve the desired effect in the product, which is often said 1+1>2, or 1+1+1>3!

Let’s talk about the combination of tranexamic acid and those ingredients!

Tranexamic acid+4msk

4MSK: also known as 4-methoxy potassium hydroxylate, is a patented ingredient of Shiseido in Japan. It is a salicylic acid derivative. It can inhibit the synthesis of melanin by hindering the activity of tyrosinase. The salicylic acid rejuvenation effect used in cosmetic medicine for gloss or chloasma, and it has been confirmed that 4MSK also has the effect of regulating the proliferation and differentiation of keratinocytes. Therefore, 4MSK can play a role in regulating the metabolism of the epidermis and promoting the elimination of melanin. clinical effect.


Tranexamic acid+Vc ethyl ether

VC ethyl ether, the standard Chinese name is 3-O-ethyl ascorbic acid, is a water-soluble vitamin C derivative, VC ethyl ether has antioxidant and whitening effects.

Tranexamic Acid + Astaxanthin

Astaxanthin structural formula

Astaxanthin: Known as one of the “strongest natural antioxidants on the earth’s surface”, it has powerful antioxidant properties, plus anti-inflammatory, sunscreen, after-sun repair, moisturizing, and damage repair effects. According to research reports, the antioxidant capacity of astaxanthin in deuterated chloroform methane is 540 times that of vitamin E. The antioxidant capacity of astaxanthin is the basis for improving skin conditions and delaying aging.

Tranexamic Acid + Niacinamide

Niacinamide is the leader in the whitening industry. Many people have different opinions about it. Some people think it is useful, and some people think it is useless. Niacinamide, also known as vitamin B3, usually accelerates the metabolism of the stratum corneum, promotes the shedding of melanin-containing keratinocytes, acts on the already produced melanin, reduces its transfer to the surface cells, promotes the synthesis of epidermal protein, and improves skin texture. In addition to whitening, there are many other effects.

In short, tranexamic acid has never been a “lone ranger” in whitening products, but it works synergistically with other ingredients to achieve the purpose of whitening.